Stephen A. Kania

Professor - Department of Comparative Medicine

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Dr. Stephen Kania obtained a master’s degree in Veterinary Microbiology from Washing State University and a  PhD in molecular microbiology from the University of Florida.   The emphasis of his research is the characterization of methicillin resistant staphylococci.  He has used genomic sequence analysis to develop a method for multilocus sequence analysis of Staphylococcus pseudintermedius, assembled the first genome of a methicillin resistant S.pseudintermedius isolate, studied the regulation of expression of antibiotic resistance genes, and is studying the potential of surface expressed proteins as vaccine candidates. Additional research interests include development of nucleic acid and peptide based diagnostic assays for infectious diseases.  Dr. Kania is currently a Professor in the Department of Biomedical and Diagnostic Sciences and Director of the Immunology Service Laboratory at the UT College of Veterinary Medicine.

Focus Areas: Molecular Diagnostics | Microbial Pathogenesis | Antibiotic Resistance | Microbial Genomic Analysis

Skills and Expertise: Analysis of Protein Expression | Flow Cytometry | Diagnostic Assay Development | Genomic Analysis

Selected Publications:

Multilocus Sequence Typing (MLST) for Characterization Staphylococcus Pseudintermedius
S.M. Solyman, C.C. Black, V. Perreten, B. Duim, E. van Duijkeren, J. A. Wagenaar, L. C. Eberlein, L.N. Sadeghi. D.A. Bemis and S.A. Kania, Journal of Clinical Microbiology, vol. 51, pp. 306-310, 2013.
Evaluation of Cefoxitin Disk Diffusion Breakpoints for Detection of Methicillin Resistance in Staphylococcus Pseudintermedius Isolated from Dogs
D.A. Bemis, R.D. Jones, R. Videla and S.A. Kania, Journal of Veterinary Diagnostic Investigation, vol. 24, no. 5, pp. 963-966, 2012.
The Role of mecA and blaZ Regulatory Elements in mecA Expression by Regional Clones of Methicillin-resistant Staphylococcus Pseudintermedius
C.C. Black, L.C. Eberlein, S.M. Solyman, R.P. Wilkes, F Hartmann, B Rohrbach, D. A. Bemis and S.A. Kania, Veterinary Microbiology, vol. 151, no. 3-4, pp. 345-353, 2011.
Molecular Analysis of Methicillin-resistant Staphylococcus Pseudintermedius of Feline Origin from Different European Countries and North America
K. Kadlec, S. Schwarz, V. Perreten, U. Gronlund-Andersson, M. Finn, C. Greko, A. Moodley, S. Kania, L. Frank, D. Bemis, A. Franco, M.Iurescia, A. Battisti, B. Duim, E. vanDuijkeren, J. Wagenaar, J. Weese, J. Fitzgerald, A. Rossano and L. Guardabassi, Journal of Antimicrobial Chemotherapy, vol. 65, no. 8, pp. 1826-1837, 2010.
Clonal Spread of Methicillin-resistant Staphylococcus Pseudintermedius in Europe and North America: An International Multicentre Study.
V. Perreten, K. Kadlec, S. Schwarz, U. Gronlund-Andersson, M. Finn, C. Greko, A. Moodley, S. Kania, L. A. Frank, D.A. Bemis, A. Franco, M. Iurescia, A. Battisti, B. Duim, J, Wagenaar, E. van Duijkeren, S. Weese, J. Fitzgerald, A. Rossano, and L. Guardabassi, Journal of Antimicrobial Chemotherapy, vol. 65, no. 6, pp. 1145-1154, 2010.
Evaluation of Susceptibility Test Breakpoints used to Predict mecA-mediated Resistance in Staphylococcus Pseudintermedius Isolated from Dogs
D.A. Bemis, R.D. Jones, L.A. Frank, and S.A. Kania , Journal of Veterinary Diagnostic Investigation, vol. 21, no. 1, pp. 53-58, 2009.
Identification of a Predominant Multilocus Sequence Type, Pulsed-field Gel Electrophoresis Cluster and Novel Staphylococcal Chromosome Cassette in Clinical Isolates of mecA-containing, Methicillin-resistant Staphylococcus Pseudintermedius
C.C. Black, S.M.,Solyman, L.C. Eberlein, D.A. Bemis, A.M. Woron, and S.A. Kania, Veterinary Microbiology, vol. 139, no. 3-4 pp. 333-338, 2009.
Risk of Colonization or Gene Transfer to Owners of Dogs with Methicillin-resistant Staphylococcus Pseudintermedius.
L.A. Frank, S.A. Kania, E.M. Kirzeder, L.C. Eberlein and D. A. Bemis, Vet. Dermatol., vol. 20, no. 5-6, pp. 496-501, 2009.
Prevalence of Oxacillin- and Multidrug-resistant Staphylococci in Clinical Samples from Dogs: 1,772 Samples (2001-2005)
R.D. Jones, S.A. Kania, B.W. Rohrbach, L.A. Frank, and D.A. Bemis, Journal of the American Veterinary Medical Association, vol. 230, no.2, pp. 221-227, 2007.
Comparison of Tests to Detect Oxacillin Resistance in Canine Isolates of Staphylococcus Intermedius, Staphylococcus Schleiferi and Staphylococcus Aureus.
D.A. Bemis, R.D. Jones, L.E. Hiatt, E.D. Ofori, B.W. Rohrbach, L.A. Frank, and S.A. Kania, Journal of Clinical Microbiology, vol. 44, no. 9, pp. 3374-3376, 2006.