John Katsaras

Joint Faculty Professor - Department of Physics & ORNL Senior Scientist and Distinguished R&D Staff

Download full publication list

John Katsaras received his undergraduate degrees (BA in Psychology and BSc in Biology) from Concordia University in Montreal (QC, Canada), and his graduate degrees (MSc and PhD in Physics) from the University of Guelph (ON, Canada). John then went on to do his postdoctoral training first, at McMaster University (ON, Canada) and then at the Centre de la Recherche Scientifique (CNRS, France). He returned to Canada in 1994 to join the neutron scattering group at the Chalk River (ON, Canada).  In 2010, John accepted a position at ORNL, as Senior Scientist and Distinguished R&D Staff in the Neutron Sciences Directorate. His primary research interest is the study of model membrane systems using a combination of experimental and computational techniques, specifically static and dynamic neutron scattering, and molecular dynamics simulations.

Focus Areas:  Model Membranes | Lipid Bilayers | Membrane Associated Proteins and Peptides | Lipid Domains and Rafts | Membrane Structure

Skills and Expertise:  Neutron, X-Ray and Light Scattering | Calorimetry | Substrate Supported Membranes | Monodisperse Vesicles | Neutron and X-Ray Holography | Molecular Dynamics

Selected Publications:

Tocopherol Activity Correlates with its Location in a Membrane: A New Perspective on the Anti-Oxidant Vitamin E
D. Marquardt, J.A. Williams, N. Kučerka, J. Atkinson, S.R. Wassall, J. Katsaras, and T.A. Harroun, Journal of the American Chemical Society, vol. 135, no. 20, pp. 7523-7533, 2013.
Bilayer Thickness Mismatch Controls Raft Size in Model Membranes
F.A. Heberle, R.S. Petruzielo, J. Pan, P. Drazba, N. Kučerka, R.F. Standaert, G.W. Feigenson, and J. Katsaras, Journal of the American Chemical Society, vol. 135, no. 18, pp. 6853-9, 2013.
Small Unilamellar Vesicles: A Platform Technology for Molecular Imaging of Brain Tumors
U. Iqbal, H. Albaghdadi, M.-P. Nieh, U.I. Tuor, Z. Mester, D. Stanimirovic, J. Katsaras, and A. Abulrob, Nanotechnology, vol. 22, no. 19, pp. 195102(1) - 195102(15), 2011.
The Functional Significance of Lipid Diversity: Orientation of Cholesterol in Bilayers is Determined by Lipid Species
N. Kučerka, D. Marquardt, T. A. Harroun, M.-P. Nieh, S. R. Wassall, and J. Katsaras, Journal of the American Chemical Society, vol. 131, no. 45, pp. 16358-9, 2009.
Cholesterol Shows Preference for the Interior of Polyunsaturated Lipid Membranes
S.J. Marrink, A.H. de Vries, T.A. Harroun, J. Katsaras, and S.R. Wassall, Journal of the American Chemical Society, vol. 130, no. 1, pp. 10-11, 2008.
Cholesterol is Found to Reside in the Centre of a Polyunsaturated Lipid Membrane
T.A. Harroun, J. Katsaras, and S.R. Wassall, Biochemistry , vol. 47, no. 27, pp. 7090-6, 2008.
Lipid Bilayer Structure Determined by the Simultaneous Analysis of Neutron and X-ray Scattering Data
N. Kučerka, J.F. Nagle, J.N. Sachs, S.E. Felle, J. Pencer, A. Jackson, and J. Katsaras, Biophysical Journal, vol. 95, no. 5, pp. 2356-2367, 2008.
Atomic Structure Holography Using Thermal Neutrons
B.Sur, R.B. Rogge, R.P. Hammond, V.N.P. Anghel, and J. Katsaras, Nature, vol. 414, no. 6863, pp. 525-7, 2001.
SANS Study of the Structural Phases of Magnetically Alignable Lanthanide-Doped Phospholipid Mixtures
M-P. Nieh, C.J. Glinka, S. Krueger, R.S. Prosser, and J. Katsaras, Langmuir , vol. 17, no. 9, pp. 2629-2638, 2001.
Rarely Observed Phase Transitions in a Novel Lyotropic Liquid Crystal System
J. Katsaras, R.L. Donaberger, I.P. Swainson, D.C. Tennant, Z. Tun, R.R. Vold, and R.S. Prosser, Physical Review Letters, vol. 78, no. 5, pp. 899-902, 1997.