Jiangang Chen

Assistant Professor - Department of Public Health

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Dr. Chen received his Bachelor of Medicine (Public Health) and Master of Medicine (Epidemiology) from Beijing Medical University.  He earned his Ph.D. in Comparative Pathology from the University of California Davis.  Dr. Chen holds an appointment as Assistant Professor in the Department of Public Health at the University of Tennessee.  He is also an Adjunct Professor in the Department of Nutrition and a faculty member in the interdisciplinary program of Comparative and Experimental Medicine at UT.  He researches potential environmental impacts on human reproduction, with a special interest in effects of endocrine disruptors (EDS) on the homeostasis of endogenous hormones. A considerable part of Dr. Chen’s research has been focused on a wide variety of synthetic compounds with intrinsic hormonal activity that may have adverse effects on human health.

Focus Areas: Reproductive Function | Endocrine Disrupting Property | Early Life Exposure | High Throughput Screening

Skills and Expertise: High throughput Screen | In vitro Chemical Testing | In vivo Exposure Evaluation

Selected Publications:

Effects of Parabens on Adipocyte Differentiation
P. Hu, X. Chen, R.J. Whitener, E.T. Boder, J.O. Jones, A. Porollo, J. Chen, and L. Zhao, Toxicological Sciences, vol. 131, no. 1, pp. 56-70, 2013.
Effects of Triclocarban on Intact Immature Male Rat: Augmentation of Androgen Action
A.J. Duleba, M.I. Ahmed, M. Sun, A.C. Gao, J. Villanueva, A.J. Conley, J.L. Turgeon, K. Benirschke, N.A. Gee, J. Chen, P.G. Green, and B.L. Lasley, Reproductive Sciences, vol. 18, no. 2, pp. 119-127, 2011.
In Vitro Biologic Activities of the Antimicrobials Triclocarban, Its Analogs, and Triclosan in Bioassay Screens: Receptor-Based Bioassay Screens
K. Chang Ahn, B. Zhao, J. Chen, G. Cherednichenko, E. Sanmarti, M. S. Denison, B. Lasley, I.N. Pessah, D. Kültz, D.P.Y. Chang, S.J. Gee, and B.D. Hammock, Environmental Health Perspectives, vol. 116, no. 9, pp. 1203-1210, 2008.
Triclocarban Enhances Testosterone Action: A New Type of Endocrine Disruptor?
J. Chen, K. Chang Ahn, N.A. Gee, M.I. Ahmed, A.J. Duleba, L. Zhao, S.J. Gee, B.D. Hammock, and B.L. Lasley, Endocrinology, vol. 149, no. 3, pp. 1173-1179, 2008.
Antiandrogenic Properties of Parabens and Other Phenolic Containing Small Molecules in Personal Care Products
J. Chena, K. Chang Ahn, N.A. Gee, S.J. Gee, B.D. Hammock, B.L. Lasley, Toxicology and Applied Pharmacology, vol. 221, no. 3, pp. 278-284, 2007.
Circulating Bioactive Androgens in Midlife Women
J. Chen, M.R. Sowers, F.M. Moran, D.S. McConnell, N.A. Gee, G.A. Greendale, C. Whitehead, S.E. Kasim-Karakas, and B.L. Lasley, The Journal of Clinical Endocrinology & Metabolism, vol. 91, no. 11, pp. 4387-4394, 2006.
Bromodichloromethane Inhibits Human Placental Trophoblast Differentiation
J. Chen, T.L. Thirkill, P.N. Lohstroh, S.R. Bielmeier, M.G. Narotsky, D.S. Best, R.A. Harrison, K. Natarajan, R.A. Pegram, J.W. Overstreet, B.L. Lasley, and G.C. Douglas, Toxicological Sciences, vol. 78, no. 1, pp. 166-174, 2004.
The Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on Chorionic Gonadotrophin Activity in Pregnant Macaques
J. Chen, L.S. Laughlin, A.G. Hendrick, K. Natarajan, J.W. Overstreet, and B.L. Lasley, Toxicology, vol. 186, no. 1-2, pp. 21-31, 2003.
Effect of Bromodichloromethane on Chorionic Gonadotrophin Secretion by Human Placental Trophoblast Cultures
J. Chen, G.C. Douglas, T.L. Thirkill, P.N. Lohstroh, S.R. Bielmeier, M.G. Narotsky, D.S. Best, R.A. Harrison, K. Natarajan, R.A. Pegram, J.W. Overstreet, and B.L. Lasley, Toxicological Sciences, vol. 76, no. 1, pp. 75-82, 2003.
Detection of Xenoestrogens in Serum After Immunoprecipitation of Endogenous Steroidal Eestrogens
K. Natarajan, J.W. Overstreet, J.M. Rogers, M.S. Denison, J. Chen, P.N. Lohstroh, D.S. McConnell, and B.L. Lasley, Environmental Health Perspectives, vol. 11, no. 8, pp. 791-795, 2002.