Dustin R. Osborne

Assistant Professor - Department of Radiology & Director - Clinical Research for the Molecular Imaging & Translational Research Program

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Dr. Osborne is an Assistant Professor in Radiology and the Director of Clinical Research for the Molecular Imaging & Translational Research Program with the University of Tennessee Graduate School of Medicine and has over 10 years of clinical and preclinical imaging experience.  Dr. Osborne earned his B.S. in Physics, M.S. in Health Physics and Ph.D. in Nuclear Engineering (Radiological Engineering) from the University of Tennessee. Dr. Osborne completed his M.S. in Health Physics while working on lung cancer imaging with Dr. David Townsend and Dr. Eoin Carney as part of the Cancer Imaging & Tracer Development Program before joining Siemens Medical Solutions where he served in a number of roles, including: Applications Support, Product Specialist and Senior Product Manager. Dr. Osborne’s research spans clinical and preclinical applications but is primarily focused on development of new applications for imaging compounds in routine clinical use and developing new imaging technologies and methods that improve the quality of patient care.

Focus Areas: Molecular Imaging | Kinetic Modeling | Data Analysis | Technology Development

Skills and Expertise: Medical Imaging Physics | PET | SPECT | CT | Experimental Design | Marketing | Project & Product Management

Selected Publications:

Whole-Body Biodistribution Of 3'-Deoxy-3'-[18 F]Fluorothymidine (18 Flt) In Healthy Adult Cats
J.A. Rowe, F. Morandi, J.S. Wall, M. Akula, S.J. Kennel, D. Osborne, E.B. Martin, G.D. Galyon, M.J. Long, A.C. Stuckey, and A.K. Leblanc , Veterinary Radiology & Ultrasound, vol. 54, no. 3, pp. 299-306, 2013.
Characterization of X-ray Dose in Murine Animals Using microCT, a New Low-Dose Detector and nanoDot Dosimeters
D.R. Osborne, S. Yan, A. Stuckey, L. Pryer, T. Richey, and J.S. Wall, PLoS ONE , vol. 7, no. 11, e49936, 2012.
Synergistic Effects of Leucine and Resveratrol on Insulin Sensitivity and Fat Metabolism in Adipocytes and Mice
A. Bruckbauer, M.B. Zemel, T. Thorpe, M.R. Akula, A.C. Stuckey, D. Osborne, E.B. Martin, S. Kennel, and J.S. Wall, Nutrition & Metabolism, vol. 9, no. 1, pp. 77, 2012.
Comparative Analysis of Peptide p5 and Serum Amyloid P Component for Imaging AA Amyloid in Mice Using Dual-Isotope SPECT
J.S. Wall, T. Richey, A. Williams, A. Stuckey, D. Osborne, E. Martin, and S.J. Kennel, Molecular Imaging and Biology, vol. 14, no. 4, pp. 402-7, 2012.
Characterization of a Small Animal SPECT Platform for use in Preclinical Translational Research
D.R. Osborne, University of Tennessee, Ph.D. Dissertation, 2011.
LaPO4 Nanoparticles Doped with Actinium-225 That Partially Sequester Daughter Radionuclides
J. Woodward, S.J. Kennel, A. Stuckey, D. Osborne, J. Wall, A.J. Rondinone, R.F. Standaert, and S. Mirzadeh, Bioconjugate Chemistry, vol. 22, no. 4, pp. 766-76, 2011.
Principles of MicroCT X-ray Computed Tomography
S. Gleason, M.J. Paulus, and D. Osborne, Molecular Imaging: Principles and Practice , Shelton, CT: People’s Medical Publishing House, 2010.
Modeling of the Point-Spread Function by Numerical Calculations in Single-Pinhole and Multi-Pinhole SPECT Reconstruction
B. Feng, M. Chen, B. Bai, A.M. Smith, D.W. Austin, R. A. Mintzer, D. Osborne, and J. Gregor, IEEE Transactions on Nuclear Science , vol. 57, no. 1, pp. 173-180, 2010.