Chris D. Cox

Professor and Head - Civil and Environmental Engineering Department

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Dr. Cox earned a bachelor’s degree in Chemical Engineering and master’s degree in Environmental Engineering from the University of Missouri, followed by a P.hD. in Environmental Engineering from Pennsylvania State University. Dr. Chris Cox is the Department Head in Civil & Environmental Engineering. He has been on the faculty of the University of Tennessee since 1991, and is a registered professional engineer in the State of Tennessee. His additional UT professional service includes Chi Epsilon Faculty Advisor; Chair, Department Curriculum Committee; and Chair, Department Assessment Committee. Dr. Cox’s research interests include bioenergy production, mathematical modeling of metabolic and genetic regulatory systems, and modeling of engineered pollution control and remediation systems.

Focus Areas: Bioenergy Production | Mathematical Modeling of Metabolic and Genetic Regulatory Systems | Modeling of Engineered Pollution Control and Remediation Systems

Skills and Expertise: Mathematical Modeling | Simulation | Exposure Assessment

Selected Publications:

Frequency Domain Analysis of Noise in Autoregulated Gene Circuits
M.L. Simpson, C.D. Cox, and G.S. Sayler, Proceedings of the National Academy of Sciences of the United States of America, vol. 100(8), pp. 4551-4556, 2003.
Engineering in the Biological Substrate: Information Processing in Genetic Circuits
M.L. Simpson, C.D. Cox, G.D. Peterson, and G.S. Sayler , Proceedings of the IEEE, vol. 92(5), pp. 848-863, 2004.
Gene Network Shaping of Inherent Noise Spectra
D. W. Austin, M. S. Allen, J. M. McCollum, R. D. Dar, J. R. Wilgus, G. S. Sayler, N. F. Samatova, C. D. Cox, and M. L. Simpson, Nature, vol. 439(7076), pp. 608-11, 2006.
The Sorting Direct Method for Stochastic Simulation of Biochemical Systems with Varying Reaction Execution Behavior
J.M. McCollum, G.D. Peterson, C.D. Cox, M. L. Simpson, and N. F. Samatova , Journal of Computational Biology and Chemistry, vol. 30(1), pp. 39-49, 2006.
Frequency Domain Analysis of Noise in Simple Gene Circuits
C.D. Cox, J.M. McCollum, D.W. Austin, M.S. Allen, R.D. Dar, and M.L. Simpson, Chaos, vol. 16(2),
Using Noise to Probe and Characterize Gene Circuits
C.D. Cox, J.M. McCollum, M.S. Allen, R.D. Dar, and M.L. Simpson, Proceedings of the National Academy of Sciences of the United States of America, vol. 105(31), pp. 10809-10814, 2008.
Noise in Biological Circuits
M.L. Simpson, C.D. Cox, M.S. Allen, J.M. McCollum, R.D. Dar, D.K. Karig, and J.F. Cooke, Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, vol. 1(2), pp. 214-225, 2009.
Transcriptional Bursting from the HIV-1 Promoter is a Significant Source of Stochastic Noise in HIV-1 Gene Expression
A. Singh, B. Razooky, C.D. Cox, M.L. Simpson, and L.S. Weinberger, Biophysical Journal, vol. 98(8), pp. L32-34, 2010.
Distribution and Regulation of Stochasticity and Plasticity in Saccharomyces Cerevisiae
R.D. Dar, D.K. Karig, J.F. Cooke, C.D. Cox, and M.L. Simpson, Chaos, vol. 20(3), 2010.
Transcriptional Burst Frequency and Burst Size are Equally Modulated Across the Human Genome
R.D. Dar, B.S. Razooky, A. Singh, T.V. Trimeloni, J.M. McCollum, C.D. Cox, M.L. Simpson, and L.S. Weinberger, Proceedings of the National Academy of Sciences of the United States of America, vol. 109(43), pp. 17454-9, 2012.