Albrecht G. von Arnim

Professor - Biochemistry and Cellular and Molecular Biology & Director - Graduate School of Genome Science and Technology

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Dr. von Arnim holds a M.S. degree in Biology from the University of Freiburg, Germany, and a Ph.D. in Biological Science (Plant Virology) from the University of East Anglia, Norwich, United Kingdom. He held a postdoctoral appointment in plant developmental biology at Yale University. Dr. von Arnim joined the University of Tennessee in the Department of Botany in 1996, and joined the Department of Biochemistry, Molecular and Cellular Biology in 2005. He is the Director of the UT-ORNL Graduate School of Genome Science and Technology and is a strong advocate for graduate training at the interface of computational and experimental biology. Dr. von Arnim’s research centers on the regulation of protein synthesis (translation), using the reference plant species Arabidopsis for genome wide studies. He also has expertise with luminescence-based biosensors for real-time in-vivo experimentation in cell and molecular biology.

Focus Areas: Translational Control of Gene Expression | Bioluminescence and Biosensors

Skills and Expertise: Molecular Genetics | Plant Biology

Selected Publications:

Known and Novel Post-Transcriptional Regulatory Sequences are Conserved across Plant Families
Vaughn, J.N., Ellingson, S.R., Mignone, F., and von Arnim, A.G. , RNA, vol. 18, no. 3, pp. 368-84, 2012.
Fluorescence-tagged Transgenic Lines Reveal Genetic Defects in Pollen Growth - Application to the eIF3 Complex
Roy, B., Copenhaver, G.P., and von Arnim, A.G. , PLoS ONE, vol. 6, no. 3, e17640, 2011.
The h Subunit of eIF3 Controls Reinitiation on mRNAs Harboring Upstream Open Reading Frames
Roy, B., Vaughn, J.N., Kim, B.H., Zhou, F., Gilchrist, M.A., and von Arnim, A.G. , RNA, vol. 16, no. 4, pp. 748-761, 2010.
YABBYs and the Transcriptional Corepressors LEUNIG and LEUNIG_HOMOLOG Maintain Leaf Polarity and Meristem Activity in Arabidopsis
M.I. Stahle, J. Kuehlich, L.A. Staron, A.G. von Arnim, and J.F. Golz, The Plant Cell, vol. 21, no. 10, pp. 3105-3118, 2009.
FIERY1 Regulates Light-mediated Repression of Cell Elongation and Flowering Time via its 3’(2’),5’-bisphosphate Nucleotidase Activity
B.H. Kim A.G. von Arnim, Plant Journal, vol. 58, no. 2, pp. 208-19, 2009.
Structure Function Studies on the Active Site of the Coelenterazine-dependent Luciferase from Renilla
J. Woo, M.H. Howell, and A.G. von Arnim, Protein Science , vol. 17, no. 4, pp. 722-35, 2008.
Imaging Protein Interactions with BRET in Plant and Mammalian Cells and Tissues
X. Xu, M. Soutto, Q. Xie, S. Servick, C. Subramanian, A.G. von Arnim, and C.H. Johnson, Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 24, pp. 10264-9, 2007.
On the Functions of the h Subunit of Eukaryotic Initiation Factor 3 in Late Stages of Translation Initiation
B.H. Kim, X. Cai, J.N. Vaughn, and A.G. von Arnim, Genome Biology, vol. 8, no. 4, pp. R60, 2007.
A Suite of Tools and Application Notes for in vivo Protein Interaction Assays using Bioluminescence Resonance Energy Transfer (BRET)
C. Subramanian, J. Woo, X. Cai, X. Xu, S. Servick, C.H. Johnson, A. Nebenführ, A.G. and von Arnim, Plant Journal, vol. 48, no. 1, pp. 138-152, 2006.
The Arabidopsis Repressor of Light Signaling, COP1, is Regulated by Nuclear Exclusion: Mutational Analysis by Bioluminescence Resonance Energy Transfer
C. Subramanian, B.H. Kim, N.N. Lyssenko, X. Xu, C.H. Johnson, and A.G. von Arnim, Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 17, pp. 6798-6802, 2004.