A Platform for Dynamic Simulation and Neuromuscular Control of Movement: Application in Predictive Simulations of Balance in Children with Cerebral Palsy
Misagh Mansouri Boroujeni
Department of Mechanical, Aerospace, and Biomedical Engineering
Thursday, November 6, 2014 at 12:40 PM
406 Min Kao Electrical Engineering and Computer Science Building
Numerical simulations are playing an important role in solving complex problems and have the potential to revolutionize medical decision making and treatment strategy. This area could greatly benefit from computational tools offering greater understanding of human movement and predictive capabilities for optimal treatment planning.
Stiff-knee gait is a troublesome neuromuscular disorder among children with cerebral palsy. Patients experiencing stiff-knee gait typically adopt energy-inefficient movements and are prone to falling and tripping. Currently, corrective procedures are based on qualitative observations during clinical examination and gait analysis, and the experience of the clinicians. Unfortunately, successful outcomes of such procedures are variable. Combining clinical movement analysis and simulation-based approaches may lead to a better understanding of biomechanical consequences of stiff-knee gait and its treatments.
In this research, a platform is created to combine musculoskeletal modeling, forward dynamic simulation, and neuromuscular control system design to test hypotheses related to balance recovery and movement control. Balance is among the most challenging tasks for patients with neuromuscular disorders such as children with cerebral palsy. Using the platform, researchers hope to develop scientific guidelines for understanding and improving balance recovery in patients with neuromuscular disorders.
Misagh Mansouri Boroujeni is a PhD candidate in Department of Mechanical, Aerospace and Biomedical Engineering at University of Tennessee. Since 2009, he has been a Graduate Research Assistant under supervision of Dr. Jeffrey Reinbolt. His work seeks to develop an integrated research foundation to understand human balance and movement control through a design, control, and simulation environment to uncover the principles that govern the coordination of muscles during normal and abnormal movement.
His graduate research has been supported by grants from the National Institute of Health, National Science Foundation and the University of Tennessee. He had some of his graduate works published in peer-reviewed journals (Journal of Biomechanics and Journal of Biosystems & Biorobotics) and presented his work in multiple conferences (ASB, BMES, IEEE SMC and WCB). His PhD work, titled “Feedback for the Brain and Body: A New Freely Available Interface between MATLAB and OpenSim” also, featured in Biomedical Computation Review Magazine, published by SimBios, in June, 2012.
Mansouri is a student member of the American Society of Mechanical Engineers (ASME), the American Society of Biomechanics (ASB) and the Biomedical Engineering Society (BMES) and a member of Honor Society of Phi Kappa Phi.