Carolina Distinguished Professor and the Robert L. Sumwalt Chair in Chemistry,
Department of Chemistry and Biochemistry,
University of South Carolina, Columbia
“Engineering of Virus Nanoparticles for Biomedical Applications”
Dr. Qian Wang’s group works on using viruses and bacteriophages as building blocks for materials development and biomedical applications.
Viruses are structurally well-defined nanoscale systems from nature. They have different shapes and a variety of sizes spanning from tens to hundreds of nanometers. It is exciting to select viruses and virus-like particles as primary building platforms for many interdisciplinary endeavors.
In Wang’s group, on the basis of the surface engineering with bioconjugation chemistry and genetic modification, they can control the self-assembly of spherical and rod-like virus particles to form 1D, 2D and 3D organized structures. These hierarchically assembled biomaterials offer a unique scaffold to investigate the drug delivery, controlled release, biosensing and cell responses. In particular, Wang would like to introduce his group’s recent studies in using plant viruses as supporting substrates to promote the osteogenesis of bone marrow derived mesenchymal stem cells.
Dr. Qian Wang received his BS degree in chemistry in 1992 from Tsinghua University. He obtained a PhD in Organic Chemistry from Tsinghua University in 1997 (supervisor: Prof. Yufen Zhao).
After postdoctoral experiences with Professor Manfred Schlosser at the University of Lausanne (1997-1999) and Professor M.G. Finn at the Scripps Research Institute (1999-2003), he started as an assistant professor at the University of South Carolina in 2003, where he is currently the Carolina Distinguished Professor and the Robert L. Sumwalt Chair of Chemistry.
The overall research objective of Wang’s laboratory focuses on using chemical biology tools to probe intracellular activities and the development of hierarchically structured nanomaterials to study the cooperative response of cells to extracellular matrixes.
Professor Wang published over 170 publications in peer reviewed journals and maintained an active research program with external funding from NSF, DoE, DoD, and NIH. He has received numerous awards, including the NSF CAREER Award (2008), the Alfred P. Sloan Research Scholar Award (2008), the Camille Dreyfus Teacher Scholar Award (2008), the CAPA Distinguished Junior Faculty Award (2008), NSF American Competitiveness Fellow Award (2009), the South Carolina Governor’s Young Scientist Award (2009), and the Fellow of the American Association for the Advancement of Science (2012).
Reception: 3:40-4:00 p.m.
Seminar: 4:00 p.m.